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While there are legitimate online Canadian pharmacies regulated by Health Canada, a government agency similar to the FDA, Canadian pharmacies that ship prescription medication to the U.S. aren’t subject to Canadian regulatory authority, according to the U.S. Department of Justice.
A spokesperson for Health Canada declined to assess the specific risks posed by these websites to Americans but did point out the Canadian government’s own warnings to its citizens about the risk of purchasing drugs on the Internet.
Ilisa Bernstein, the FDA’s deputy director at the Office of Compliance, also urges caution. “I think it is safe to say that when you buy over the Internet there is a chance that you are going to get a substandard or counterfeit drug,” she says. “There is little oversight of the global online drug marketplace. There are some pharmacies that are legitimately doing business online in the U.S. These pharmacies abide by federal and state laws in the U.S.”
In one recent study published in the online journal PLoS One, researchers ordered several brand-name medications through various pharmacies, some they thought were legitimate and others they suspected were not. Of the 152 drugs received, they found that three orders of Viagra (sildenafil) failed in testing and were probably counterfeit. And another 31 orders (20 percent) weren’t filled with the drug written on the prescription. Some online pharmacy websites replaced brand-name medication, such as Nexium and Lipitor, with other drugs that the researchers reported were probably generics. We’re usually a big fan of generics but only when they’ve been officially approved by the FDA. (Nexium and Lipitor don’t have approved generics in the U.S. market yet.) Since the researchers determined that the generics couldn’t be compared with the brand-name drugs, they weren’t tested to determine if they were counterfeit.
And in 2008, the European Alliance for Access to Safe Medicines, an industry-funded group, ordered drugs from 116 websites. They included some that were suspect, such as those identified by e-mail solicitations and web searches using terms like “online pharmacy” and “cheap medicines.” The study found that over 90 percent of the websites didn’t require prescriptions to sell prescription-only drugs, and nearly 85 percent didn’t provide information linking them to a verifiable walk-in pharmacy. Tests also found that 62 percent of the medication received was counterfeit, substandard, or in a generic form not licensed by the original developer.
Technically, it’s illegal for people in the U.S. to import prescription medication into the country. But the law is generally not enforced when people buy 90-day supplies for personal use, particularly if the drug is for a serious condition for which treatment might not be available here. If you do decide to order online, our medical experts suggest the following six measures to stay safe:
1. Stick with online pharmacies associated with legitimate walk-in stores in the U.S. CVS.com, Target.com, and Walmart.com, for example. Even your local independent pharmacy probably has a website that can accept prescription orders and refills.
2. Look for the VIPPS symbol. For other pharmacies, check with Verified Internet Pharmacy Practice Sites, or VIPPS, a voluntary program the NABP set up in 1999. Internet pharmacies that meet the criteria can carry the VIPPS seal of approval. Among the requirements: pharmacies must be in the U.S.; they can dispense only FDA-approved medication; prescriptions they fill must be the result of a doctor-patient relationship; and they must list their physical location.
3. Try another source. LegitScript.com uses NABP standards to assess drugstores that don’t participate in VIPPS.
4. Confirm state approval. Make sure an online pharmacy is registered to do business in your state. To find out, do a search for, say, “California board of pharmacy” and follow the links to verify that the site is legitimate.
5. Follow up. If you’re still unsure, NABP lists sites it doesn’t recommend, which can be found here. Scroll down and click on “Buying Medicine Online,” then “Not Recommended Sites.”
6. Go local. Your best resource is a trusted pharmacist or pharmacy distribution program. Although rare, counterfeit drugs have been found in the U.S. supply chain.
Bottom line: Given the high risk of ordering medication from foreign websites, stick with well-known websites, walk-in pharmacies, and pharmacy chains in the U.S. To save money, switch to generics whenever possible, look for discount programs, and ask your doctor or pharmacist about other ways to reduce your costs.
These materials are made possible by a grant from the state Attorney General Consumer and Prescriber Education Grant Program, which is funded by the multi-state settlement of consumer-fraud claims regarding the marketing of the prescription drug Neurontin (gabapentin).
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